Thesis vs Alpha Brain Nootropics - Neuropedia

Thesis vs Alpha Brain Nootropics

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Brain fog? Fatigue? Sluggish thinking? Easily distracted? 

Want increased Focus? Motivation?

Common symptoms that many of us have struggled with for years. What if there was a way to blow through all of this and truly maximize your brain’s potential? 

Enter nootropics. 

Nootropics are a class of ingredients designed to improve cognitive functions such as attention, memory, learning, and even creativity. The key parts of the brain targeted by many nootropic compounds are acetylcholine and dopamine; these influence your attention span, motivation levels, and ability to think and plan.

There are now dozens of over-the-counter products that claim to support your ability to focus, think, and plan. Many contain exotic sounding ingredients making it hard for most people to easily determine where the ingredients were sourced and their effectiveness. 

In this article, we are going to review two of the most popular nootropic supplements on the market, Thesis and Alpha Brain. Both have excellent reputations and contain thousands of five-star reviews.   



Thesis was founded on the basic premise that no two people are the same. In the same way coffee, exercise regimes or diets have different impacts on different people, you shouldn’t expect a supplement that you pick-up off-the-shelf to work for everybody.

Thesis has designed a system that takes you through a quiz and a 4-week trial phase to help you find the right nootropic formulas for your brain. This allows you to try multiple formulas and find one (or more!) that works for you. 

Each blend has different ingredients to target areas where your mind might need some help. One of the formulas, Energy, contains NALT, a more bioavailable version of Tyrosine to support your ability to think and plan. It also includes Citicoline (Choline donor) to support learning and memory, among other ingredients. Other formulas include Motivation, Clarity, Creativity, and Logic. You’ll have a chance to try 27 ingredients across the formulas to see how you respond to different ingredients. The process of trying multiple blends gives you a better chance of finding the one that works best for you.

Just like coffee can make some people jittery and others energized, you’ll likely find each of the blends have a different effect on you. (Fun fact: coffee is actually a nootropic!)

Thesis offers free coaching sessions with nootropic experts to help you on your journey and answer the questions you may have along the way. 

After the trial period, you can customize your boxes to have only the blends that work best for you. Nine out of ten people report finding at least one formulation, while most people generally find at least two or three.

To see which formulations are recommended for you take this quiz here!


Thesis offers two pricing options:

  • One-time purchase for $119 (4-week supply)
  • Subscription purchase for $79 (4-week supply)

They also offer a 30-day money back guarantee and you can cancel your subscription anytime.


  • Unique system that allows you to quickly test multiple formulas (27 different ingredients) and find the ones that work best for your brain
  • Free coaching sessions offered
  • Customizable subscription box
  • Caffeine and caffeine free options
  • Full ingredient transparency
  • Third party lab tested
  • Free shipping
  • 30 day, full refund, risk free trial


  • Longer trial process
  • Slightly pricier option

Alpha Brain


Alpha Brain is another popular nootropic option that is a single blend. Alpha Brain works by aiding neurotransmitter production and increasing alpha brain waves. The formula is broken down into 3 parts:

  • Flow Blend and Cat’s Claw to promote alpha brain production
  • Focus Blend to optimize acetylcholine levels
  • Fuel Blend to optimize neural communication

These include ingredients like L-Theanine and L-Tyrosine to support dopamine production and Alpha-GPC and Huperzia Serrata (Huperzine A) to increase acetylcholine levels in the brain. 


Alpha Brain has two pricing options:

  • One-time purchase for $79 (45 day supply)
  • Subscription purchase for $68 (45 day supply)

They also offer a 30-day money back guarantee and you can cancel your subscription anytime.


  • Cheaper option
  • Simple trial process


  • One size fits all approach makes it more hit or miss based on your response to the specific ingredients
  • Proprietary formula – they don’t list the quantity on most ingredients
  • No caffeine option 
  • No coaching offered
  • No free shipping

The Verdict

Both Thesis and Alpha Brain are great supplements for improving focus, clarity and motivation. . 

Alpha Brain has some highly researched ingredients that support dopamine and acetylcholine levels. 

Thesis’ unique trial process gives you the chance to find something that works right for you. That’s make or break for whether you find success with nootropics. 

Some people respond really well to Alpha-GPC and others respond better to Citicoline. With Alpha Brain, you are only getting to try Alpha-GPC and there is a possibility it may not work for you. Some people prefer more stimulating ingredients to achieve focus, while others prefer to be in a calm state. 

Alpha Brain only offers one mode that may not work for everyone, while Thesis gives you the chance to test across the spectrum. 

If you are interested in trying nootropics to get more energy, focus, and flow, Thesis can help you find a formulation that works for you.

Take this short quiz to get their best deal of the year and start your trial phase.

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